The BIG question
These podcast episodes discuss the big question of what aging is.
What is the initial cause?
What processes are activated by this cause?
And how do these processes lead to disease?

A good episode to start:
Episodes on the big question
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Alex Wolf – The Aging vs. Cancer Trade-off
Many believe that ageing and cancer are the same process, but several lines of evidence suggest that ageing and age-related diseases might have evolved to prevent cancer.
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Josh Mitteldorf – Aging as an Altruistic Programme
Aging is clearly detrimental, but perhaps our sacrifice has an unexpected benefit to our species. Would life be sustainable without aging, or would we all be undergoing obligatory calorie restriction?
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David Gems – The Evolution of Aging
In this episode David Gems discusses how his journey has led to his understanding of why aging might evolve despite its detrimental effects. David’s book ‘On Aging’ will be available around September 2026.